A febrile child with suspected systemic JIA has ferritin 1,420 ng/mL, platelets 170 ×10⁹/L, AST 62 U/L, triglycerides 130 mg/dL and fibrinogen 4.0

Question

A febrile child with suspected systemic JIA has ferritin 1,420 ng/mL, platelets 170 ×10⁹/L, AST 62 U/L, triglycerides 130 mg/dL and fibrinogen 4.0 g/L. How do the 2016 EULAR/ACR/PRINTO MAS criteria classify this pattern?

Accepted Answer

It meets MAS criteria: ferritin above 684 plus platelet and AST thresholds

Answer

It fails classification because fibrinogen must be at or below 3.6 g/L in every case

Answer

It fails classification because triglycerides must exceed 156 mg/dL in every case

Answer

It meets classification only if bone-marrow haemophagocytosis is demonstrated

Answer

It meets classification because ferritin alone is sufficient above 1,000 ng/mL

Systemic juvenile idiopathic arthritis — SCE Rheumatology MCQ

A febrile child with suspected systemic JIA has ferritin 1,420 ng/mL, platelets 170 ×10⁹/L, AST 62 U/L, triglycerides 130 mg/dL and fibrinogen 4.0 g/L. How do the 2016 EULAR/ACR/PRINTO MAS criteria classify this pattern?