Eosinophilic granulomatosis with polyangiitis — SCE Rheumatology MCQ

Correct answer: E — Cardiac involvement

Cardiac involvement is the single best answer because asthma with eosinophilia, sinus disease and vasculitic neuropathy suggests EGPA. The stem is testing complication screening, not isolated recall, so the relevant clinical pattern and risk context determine the answer. Migraine is less suitable because it fits a different clinical pattern or a different treatment threshold; Sarcoidosis, Aspirin monotherapy and Etanercept do not address the key discriminator in this vignette. Clinical pearl: in SCE-style rheumatology questions, autoantibodies, imaging and synovial fluid findings should be interpreted with the whole phenotype.

Reference: BSR/EULAR vasculitis recommendations; NICE technology appraisals; BNF