Mixed connective tissue disease — SCE Rheumatology MCQ
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Correct answer: D — Annual PFTs, echocardiography, NT-proBNP and DETECT in eligible patients
Explanation lettering: D = shown as A · C = shown as B · E = shown as C · B = shown as D · A = shown as E
B is correct. BSR recommends annual PAH screening in all systemic-sclerosis patients using PFTs, echocardiography and NT-proBNP, with DETECT in suitable people. HRCT assesses ILD rather than serving as routine PAH surveillance; universal catheterisation is invasive, while symptom-triggered echocardiography misses clinically silent disease.
Reference: 2024 British Society for Rheumatology systemic sclerosis guideline: executive summary. https://academic.oup.com/rheumatology/article/63/11/2948/7750185