skip to main content

Psoriatic arthritis with IBD — SCE Rheumatology MCQ

Instant feedback + full explanation. One question, done properly.

HardSpondyloarthropathiesPsoriatic arthritis with IBDSCE Rheumatology

A patient with active rheumatoid arthritis weighs exactly 100 kg and is starting intravenous abatacept. Which induction and maintenance schedule matches the UK SmPC?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Give 750 mg at weeks 0, 2 and 4, then 750 mg every 4 weeks

Explanation lettering: C = shown as A · E = shown as B · A = shown as C · B = shown as E

D is correct. Intravenous abatacept is infused over 30 minutes using fixed weight bands: below 60 kg receives 500 mg, 60 kg through 100 kg inclusive receives 750 mg, and only weight above 100 kg receives 1,000 mg. After the first infusion, doses are repeated at weeks 2 and 4 and then every four weeks. The exact 100 kg boundary therefore remains in the 750 mg band.

Reference: Orencia 250 mg powder for infusion SmPC: https://www.medicines.org.uk/emc/product/334/smpc