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SLE pregnancy anti-Ro — SCE Rheumatology MCQ

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ModeratePregnancy in rheumatic disease and rare conditionsSLE pregnancy anti-RoSCE Rheumatology

A 30-year-old woman with SLE is 10 weeks pregnant and anti-Ro positive. Examination shows disease is quiescent on hydroxychloroquine. Investigations show renal function and urine PCR are normal. What is the most appropriate management?

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Correct answer: A — Continue hydroxychloroquine and arrange fetal cardiac surveillance

Continue hydroxychloroquine and arrange fetal cardiac surveillance is the most appropriate pregnancy-specific management strategy. The alternatives include teratogenic therapy, inadequate thromboprophylaxis or unsafe delay. Rheumatic disease pregnancy planning should occur before conception whenever possible.

Reference: BSR pregnancy prescribing guideline; EULAR pregnancy and rheumatic disease recommendations; BNF