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RS3PE syndrome — SCE Rheumatology MCQ

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HardPregnancy in rheumatic disease and rare conditionsRS3PE syndromeSCE Rheumatology

A patient with suspected Sjögren disease has sicca symptoms, negative anti-Ro antibodies and equivocal examination. What can salivary-gland ultrasound contribute?

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Correct answer: C — Supports diagnosis alongside serology and possible labial biopsy

Salivary-gland ultrasound is a useful non-invasive adjunct when the diagnosis remains uncertain. It can increase or reduce suspicion but is not currently a substitute for anti-Ro testing or labial salivary-gland histology within adult classification.

Reference: BSR guideline for adult and juvenile-onset Sjögren disease (Published May 2024): https://academic.oup.com/rheumatology/article/64/2/409/7645909; EULAR recommendations for management of Sjögren syndrome (Published 2020): https://ard.bmj.com/content/79/1/3