skip to main content

Enthesitis-related arthritis — SCE Rheumatology MCQ

Instant feedback + full explanation. One question, done properly.

HardPaediatric rheumatologyEnthesitis-related arthritisSCE Rheumatology

A patient with active axial spondyloarthritis needs targeted therapy and has recurrent anterior uveitis. Which class feature should influence selection?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: APrefer a monoclonal TNF inhibitor for recurrent uveitis

When recurrent uveitis drives treatment choice, monoclonal TNF inhibitors are preferred over etanercept and may be favoured over IL-17 inhibitors. The final choice also incorporates axial activity, psoriasis, inflammatory bowel disease and safety.

Reference: 2025 BSR guideline for axial spondyloarthritis with biologic and targeted synthetic DMARDs (Published April 2025): https://academic.oup.com/rheumatology/article/64/6/3242/8108015; NICE NG65: spondyloarthritis in over 16s — recommendations (Updated June 2017): https://www.nice.org.uk/guidance/ng65/chapter/Recommendations