skip to main content

Axial spondyloarthritis with psoriasis — SCE Rheumatology MCQ

Instant feedback + full explanation. One question, done properly.

HardSpondyloarthropathiesAxial spondyloarthritis with psoriasisSCE Rheumatology

A 40-year-old woman has active axial disease, extensive psoriasis and raised CRP after NSAID failure. Examination shows limited spinal movement and enthesitis. Investigations show infection screening is negative. What is the most appropriate biologic?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Secukinumab

IL-17 inhibition can treat active axial spondyloarthritis and psoriasis when targeted therapy criteria are met. Rituximab and belimumab are not standard therapies for axial spondyloarthritis. Skin phenotype may favour IL-17 pathway treatment.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/musculoskeletal-conditions