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Biologic infection — SCE Rheumatology MCQ

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EasyRheumatological pharmacologyBiologic infectionSCE Rheumatology

A 60-year-old man on adalimumab develops fever and productive cough. Examination shows crackles are present at the right base. Investigations show CRP is 122 mg/L and chest radiograph shows consolidation. What is the most appropriate management?

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Correct answer: EWithhold biologic and treat infection

Withhold biologic and treat infection is the safest management step for this treatment-related scenario. The alternatives either continue a potentially harmful drug, omit essential monitoring, or address the wrong risk. Shared-care DMARD prescribing depends on clear monitoring thresholds and rapid communication with rheumatology.

Reference: BNF; SPS DMARD monitoring guidance; BSR DMARD prescribing guideline