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Chromoblastomycosis — DTM&H MCQ

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HardDermatological tropical conditionsChromoblastomycosisDTM&H

A small, localised chromoblastomycosis plaque is confirmed before extensive lymphoedema develops. Which management approach is most appropriate?

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Correct answer: D — Use prolonged itraconazole or terbinafine with selected local lesion therapy

The best answer is “Use prolonged itraconazole or terbinafine with selected local lesion therapy”. WHO identifies itraconazole and terbinafine as effective systemic therapies; small lesions may also benefit from selected surgery, cryotherapy or heat-based treatment. Topical therapy over only four weeks is inadequate for a deep chronic mycosis. Amphotericin and flucytosine have been used in selected circumstances but are not routine first choices, and systemic treatment before local surgery reduces recurrence risk. Treatment is prolonged, and larger disease has poorer outcomes.

Reference: WHO, Chromoblastomycosis fact sheet: https://www.who.int/news-room/fact-sheets/detail/chromoblastomycosis