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Broad-spectrum antibiotics — DFSRH MCQ

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EasyPharmacologyBroad-spectrum antibioticsDFSRH

A 22-year-old combined pill user is prescribed amoxicillin for sinusitis. She has no vomiting or diarrhoea and has taken pills correctly. What would you advise this patient?

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Correct answer: E — No additional contraception is required because of amoxicillin alone

Non-enzyme-inducing antibiotics such as amoxicillin do not reduce CHC effectiveness by themselves. Vomiting or severe diarrhoea would change advice. The old blanket antibiotic warning is a common misconception.

Reference: BNF; FSRH Drug Interactions with Hormonal Contraception Guidance; UKMEC 2025