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CHC restart after ulipristal — DFSRH MCQ

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ModerateCombined hormonal contraceptionCHC restart after ulipristalDFSRH

A 26-year-old woman took ulipristal acetate emergency contraception today after missed CHC pills. She asks when to restart her combined pill. What would you advise this patient?

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Correct answer: E — Wait 5 days before restarting CHC and use condoms meanwhile

Progestogen exposure can reduce the effect of ulipristal, so CHC should be delayed for 5 days after UPA. Immediate restart is appropriate after levonorgestrel EC rather than UPA. Condoms are needed during the delay and after restart until protection is established.

Reference: FSRH Combined Hormonal Contraception Guideline; UKMEC 2025; BNF