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Rifampicin interaction — DFSRH MCQ

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EasyPharmacologyRifampicin interactionDFSRH

A 28-year-old woman starting rifampicin for tuberculosis uses a combined pill. She wants reliable contraception during treatment. What is the most appropriate contraceptive method?

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Correct answer: E — Copper IUD

Rifampicin is a strong enzyme inducer and reduces effectiveness of CHC, POP and implant. Copper IUD is not affected and is highly effective. DMPA would also be a suitable non-IUD option.

Reference: BNF; FSRH Drug Interactions with Hormonal Contraception Guidance; UKMEC 2025