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Mycoplasma genitalium — DFSRH MCQ

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ModerateSTIsMycoplasma genitaliumDFSRH

A 28-year-old man has persistent non-gonococcal urethritis after doxycycline. Gonorrhoea and chlamydia NAATs are negative. What is the most appropriate investigation?

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Correct answer: D — Mycoplasma genitalium NAAT with resistance testing where available

Persistent urethritis after initial treatment should prompt consideration of Mycoplasma genitalium, ideally with resistance testing. Urine dipstick alone does not identify the pathogen. Avoid repeated empirical antibiotics without diagnosis where possible.

Reference: BASHH Guidelines; NICE CKS; UKHSA STI guidance; BNF