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Gonorrhoea treatment — DFSRH MCQ

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HardSTIsGonorrhoea treatmentDFSRH

A 24-year-old man has urethral discharge and NAAT is positive for gonorrhoea. Culture susceptibility is not yet available. What is the most appropriate management?

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Correct answer: BCeftriaxone intramuscular treatment and partner notification

The best answer is “Ceftriaxone intramuscular treatment and partner notification”. When susceptibility is unknown, ceftriaxone intramuscular therapy is standard for gonorrhoea. Doxycycline alone would treat chlamydia but not gonorrhoea. Culture, partner notification and test-of-cure arrangements are important. The diagnosis and management depend on the exposure sites, symptom pattern, pregnancy status, microbiology and need for partner notification. Empirical treatment may be appropriate when delay risks complications, but samples should be collected where possible. Advice about abstinence or condoms continues until treatment and partner management have made reinfection unlikely.

Reference: BASHH, Gonorrhoea 2025 updated guideline: https://www.bashh.org/resources/136/gonorrhoea_2025_updated_guideline/