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Flucloxacillin administration — GPhC CRA MCQ

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HardInfection ManagementFlucloxacillin administrationGPhC CRA

A patient receives flucloxacillin 500mg four times daily for cellulitis. He asks whether he can take it with meals because he often feels sick with antibiotics. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Take it on an empty stomach where possible, while completing the course

Flucloxacillin is usually taken on an empty stomach for optimal absorption. The patient should complete the prescribed course and seek review if cellulitis worsens or systemic symptoms develop. Taking the full daily dose at once would not maintain adequate exposure.

Reference: BNF