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Prochlorperazine Parkinson's — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsProchlorperazine Parkinson'sGPhC CRA

A patient with Parkinson's disease asks to buy treatment for nausea. A colleague suggests prochlorperazine, but the patient's medication includes co-careldopa. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Seek prescriber advice for an antiemetic suitable in Parkinson's disease

Dopamine-blocking antiemetics such as prochlorperazine and metoclopramide can worsen Parkinson's symptoms. A safer antiemetic choice should be made with appropriate clinical advice. Stopping Parkinson's medicines can also cause significant deterioration.

Reference: BNF; NICE CKS