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Opioid constipation — GPhC CRA MCQ

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EasyCNS TherapeuticsOpioid constipationGPhC CRA

A patient starts modified-release morphine for cancer pain and asks whether constipation is likely. No laxative is on the prescription. What would you advise the patient?

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Correct answer: EConstipation is common and a regular stimulant laxative should be considered

Opioid-induced constipation is common and does not usually improve with tolerance. Prophylactic laxative therapy is often needed unless contraindicated. The patient should not reduce analgesic dosing independently or use antidiarrhoeal medicines for prevention.

Reference: BNF; NICE CKS