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Sildenafil and alpha blocker — GPhC CRA MCQ

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ModerateDrug InteractionsSildenafil and alpha blockerGPhC CRA

A patient taking doxazosin modified-release for benign prostatic enlargement asks to buy sildenafil. He reports dizziness on standing. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — The combination can increase symptomatic hypotension risk

Both sildenafil and alpha-blockers can lower blood pressure, and postural symptoms increase concern. The pharmacist should assess suitability carefully and may need prescriber advice depending on dose and symptoms. The patient should be counselled on hypotension risk.

Reference: BNF