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Dabigatran dyspepsia — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsDabigatran dyspepsiaGPhC CRA

A patient taking dabigatran for atrial fibrillation reports troublesome indigestion since starting it. They ask whether to open the capsules and mix the contents with yoghurt. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: ASwallow the capsules whole and seek review for persistent dyspepsia

Dabigatran capsules should be swallowed whole because opening or chewing can increase exposure and bleeding risk. Dyspepsia is a recognised adverse effect and should be reviewed if persistent or severe. Repackaging or opening capsules may also compromise safe administration.

Reference: BNF