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Pioglitazone heart failure — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsPioglitazone heart failureGPhC CRA

A patient with type 2 diabetes and symptomatic heart failure presents a new prescription for pioglitazone. The pharmacy record shows furosemide and bisoprolol. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Query the prescription because pioglitazone is unsuitable in heart failure

Pioglitazone can cause fluid retention and is contraindicated in heart failure. The pharmacist should query the prescription with the prescriber before supply. Treatment alternatives require clinical review rather than pharmacy substitution.

Reference: BNF