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Enoxaparin renal dosing — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentEnoxaparin renal dosingGPhC CRA

A patient discharged after pulmonary embolism has enoxaparin injections while awaiting anticoagulation review. The discharge summary lists creatinine clearance as 25mL/min. What is the most appropriate alternative?

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Correct answer: A — Query whether renal dose adjustment or alternative anticoagulation is needed

Low molecular weight heparins are renally cleared to varying degrees, and dose adjustment may be required in renal impairment. A creatinine clearance of 25mL/min should prompt careful checking before supply. The pharmacist should not adjust the dose independently without prescriber agreement.

Reference: BNF