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SGLT2 inhibitor sick day advice — GPhC CRA MCQ

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EasyEndocrine TherapeuticsSGLT2 inhibitor sick day adviceGPhC CRA

A patient taking dapagliflozin for type 2 diabetes develops vomiting and reduced oral intake due to gastroenteritis. He asks whether to continue his tablets. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Temporarily withhold dapagliflozin during acute illness and seek diabetes advice

SGLT2 inhibitors can increase the risk of diabetic ketoacidosis during acute illness, dehydration, or reduced carbohydrate intake. Sick-day advice commonly includes temporarily withholding the drug and seeking clinical advice, especially if unwell. The patient should maintain hydration and follow local diabetes guidance.

Reference: BNF; NICE CKS