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Hepatic impairment and statins — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentHepatic impairment and statinsGPhC CRA

A patient with active liver disease and unexplained persistently raised transaminases presents a new prescription for atorvastatin. The indication is primary prevention. What is the most appropriate alternative?

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Correct answer: A — Query the prescription before dispensing

Statins require caution and are contraindicated in active liver disease or unexplained persistent transaminase elevations. The pharmacist should clarify the clinical context before supply. Herbal products do not mitigate statin-related hepatic concerns and may add risk.

Reference: BNF