Metformin renal impairment — GPhC CRA MCQ
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Correct answer: A — Intracranial hypertension
Systemic tetracyclines and isotretinoin are avoided together because both are associated with benign intracranial hypertension. Persistent headache, visual symptoms, nausea or pulsatile tinnitus require urgent assessment. Acne treatment should be coordinated with the dermatology team rather than self-sourced alongside isotretinoin.
Reference: https://bnf.nice.org.uk/interactions/