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Opioid overdose risk — GPhC CRA MCQ

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HardCNS TherapeuticsOpioid overdose riskGPhC CRA

A carer asks for advice because a patient using morphine solution is unusually drowsy with slow breathing after a dose increase yesterday. The patient is difficult to wake. What is the most appropriate action?

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Correct answer: E — Call emergency services for possible opioid toxicity

Marked drowsiness with slow breathing after opioid dose escalation suggests possible opioid toxicity. This requires emergency assessment and may need naloxone and supportive care. Waiting overnight or giving more opioid could be dangerous.

Reference: BNF