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Morphine renal impairment — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentMorphine renal impairmentGPhC CRA

An opioid-naive patient with chronic non-cancer pain receives a fentanyl 25 microgram/hour patch. What should the pharmacist do?

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Correct answer: DQuery the patch; opioid tolerance is not established

Transdermal fentanyl is potent, slow to titrate and inappropriate for opioid-naive patients because respiratory depression may be fatal. Patches must not be cut or heated. The prescription requires clarification and a safer initiation strategy before supply.

Reference: BNF: fentanyl: https://bnf.nice.org.uk/drugs/fentanyl/