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Paracetamol liver disease — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentParacetamol liver diseaseGPhC CRA

A patient with known alcohol-related liver disease asks to buy the maximum pack of paracetamol for daily headaches. He drinks alcohol most days. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Refer for pharmacist or prescriber assessment before recommending regular paracetamol

Paracetamol can be used in many patients but liver disease and regular alcohol intake require careful assessment of dose and duration. The patient also needs review for frequent headaches and risk of duplicate paracetamol-containing products. Maximum-dose long-term self-treatment would be inappropriate.

Reference: BNF; NICE CKS