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Domperidone cardiac risk — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsDomperidone cardiac riskGPhC CRA

A patient asks to buy domperidone for nausea. Her record shows long QT syndrome and amiodarone therapy. What is the most appropriate action?

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Correct answer: A — Do not supply and refer for medical advice

Domperidone is associated with cardiac risk including QT prolongation and is unsuitable in patients with significant cardiac conduction risk or interacting medicines. Amiodarone also carries QT-related risk, so the combination is concerning. The patient should be referred for safer management.

Reference: BNF; MHRA