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ACE inhibitor angioedema — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyACE inhibitor angioedemaGPhC CRA

A patient taking lisinopril develops swelling of the lips and tongue. Breathing feels tight and symptoms are progressing while in the pharmacy. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Call emergency services and treat as possible angioedema

ACE inhibitors can cause angioedema, which may threaten the airway. Progressive tongue or lip swelling with breathing symptoms requires emergency assessment. Further ACE inhibitor doses should not be taken unless a clinician has fully assessed the situation.

Reference: BNF; NICE CKS