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Metformin contrast illness — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentMetformin contrast illnessGPhC CRA

A patient taking metformin is discharged after an acute kidney injury related to dehydration. The eGFR is still unstable and the repeat prescription includes full-dose metformin. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Query whether metformin should remain withheld until renal function stabilises

Metformin safety depends on renal function and acute illness can increase lactic acidosis risk. After acute kidney injury, continuation or restarting should be clinically reviewed. The pharmacist should not make independent antidiabetic substitutions.

Reference: BNF; NICE CKS