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DMARD infection advice — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsDMARD infection adviceGPhC CRA

A patient taking azathioprine for an autoimmune condition asks whether to continue it while febrile with a productive cough and feeling systemically unwell. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Seek urgent prescriber advice because infection and immunosuppression need assessment

Azathioprine is immunosuppressive and significant infection symptoms require clinical assessment. The patient may need investigation, temporary treatment adjustment, or antimicrobial therapy depending on severity and local advice. The pharmacist should not recommend unsupervised dose changes or leftover antibiotics.

Reference: BNF; NICE CKS