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Methotrexate counselling — GPhC CRA MCQ

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EasyPatient Counselling and Pharmaceutical CareMethotrexate counsellingGPhC CRA

A patient starting methotrexate for rheumatoid arthritis is also prescribed folic acid. She asks why the methotrexate box has a weekly warning label. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Take methotrexate once weekly on the agreed day and report sore throat or mouth ulcers

Methotrexate for rheumatoid arthritis is taken once weekly, and daily dosing errors can be serious. Patients should know their weekly day, folic acid schedule, monitoring requirements, and toxicity symptoms such as mouth ulcers, sore throat, or unexplained bruising. Interacting medicines should be checked before use.

Reference: BNF; NICE CKS