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Valproate risk materials — GPhC CRA MCQ

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EasyAdverse Drug Reactions and Drug SafetyValproate risk materialsGPhC CRA

A patient taking valproate says she has not received a patient card and does not remember any discussion about pregnancy risk. She is 28 years old. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EProvide risk materials and refer for Pregnancy Prevention Programme review

Valproate is associated with serious harm in pregnancy and requires risk minimisation measures. Patients of childbearing potential should receive appropriate materials and specialist review under the Pregnancy Prevention Programme where applicable. Abrupt stopping can risk seizure or relapse and should not be advised without specialist input.

Reference: MHRA; BNF