Hypertension first-line treatment — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHypertension first-line treatmentGPhC CRA

A 58-year-old man has repeated clinic blood pressure readings above target and no compelling comorbidities. He has not previously taken antihypertensive treatment and his renal function is normal. What is the most appropriate alternative?

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Correct answer: A — Amlodipine

For uncomplicated hypertension in a person aged 55 years or over, a calcium-channel blocker is a usual first-line option. Ramipril would be more typical as first-line treatment in younger adults, unless there are other indications. Doxazosin, beta-blockers, and spironolactone are generally later-line or indication-specific options. The keyed option is amlodipine, a calcium-channel blocker appropriate at this step.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-27