skip to main content

Statin myopathy — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

EasyAdverse Drug Reactions and Drug SafetyStatin myopathyGPhC CRA

A patient taking atorvastatin reports new severe muscle pain, weakness and dark urine after starting clarithromycin. He asks if he can finish the antibiotic first. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Refer urgently for assessment of possible rhabdomyolysis

Severe muscle symptoms with dark urine suggest possible rhabdomyolysis, especially with a statin interaction. This requires urgent clinical assessment, including creatine kinase and renal function. Continuing the interacting combination without review could worsen harm.

Reference: BNF