skip to main content

ACE inhibitor and potassium supplement — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateDrug InteractionsACE inhibitor and potassium supplementGPhC CRA

A patient taking ramipril and spironolactone asks to buy potassium tablets because of leg cramps. His renal function is reduced. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Potassium supplements can increase hyperkalaemia risk with ramipril and spironolactone

ACE inhibitors and potassium-sparing diuretics both increase potassium. Adding potassium supplements without blood tests and clinical review may cause dangerous hyperkalaemia, especially in renal impairment. Leg cramps should be assessed rather than self-treated with potassium.

Reference: BNF