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Metoclopramide safety — GPhC CRA MCQ

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ModerateGastro-intestinal TherapeuticsMetoclopramide safetyGPhC CRA

A 19-year-old woman is prescribed metoclopramide for nausea after migraine. She reports neck stiffness and eye deviation after the first dose. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EStop and seek urgent medical advice for possible acute dystonia

Metoclopramide can cause extrapyramidal reactions such as acute dystonia, especially in younger patients. Symptoms such as neck stiffness and oculogyric crisis require prompt medical advice. Rechallenge without review is unsafe.

Reference: BNF