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Carbimazole agranulocytosis — GPhC CRA MCQ

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EasyEndocrine TherapeuticsCarbimazole agranulocytosisGPhC CRA

A 46-year-old woman started carbimazole for Graves' disease. She asks what symptoms should make her seek urgent help. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Report sore throat, fever or mouth ulcers urgently

Carbimazole can rarely cause bone marrow suppression including agranulocytosis. Sore throat, fever or mouth ulcers require urgent medical advice and blood count assessment. Patients should be counselled at initiation.

Reference: BNF; NICE CKS