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Metoclopramide renal dose — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentMetoclopramide renal doseGPhC CRA

A frail 86-year-old woman with eGFR 20 mL/min/1.73 m² is prescribed metoclopramide 10 mg three times daily for nausea. She has Parkinson's disease. What is the most appropriate action?

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Correct answer: E — Query suitability because renal impairment and Parkinson's disease increase risk

Metoclopramide requires caution and dose consideration in renal impairment and is generally avoided or used cautiously in Parkinson's disease due to extrapyramidal effects. The scenario warrants prescriber review. Long-term use is also restricted due to neurological risks.

Reference: BNF