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Valproate dispensing safety — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyValproate dispensing safetyGPhC CRA

A pharmacy receives a repeat prescription for valproate for a woman aged 32. The patient says she has not seen a specialist for two years and does not recall signing risk forms. What is the most appropriate action?

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Correct answer: A — Supply with urgent referral to prescriber or specialist to confirm pregnancy prevention safeguards

Valproate has significant pregnancy-related risks and requires ongoing specialist review and pregnancy prevention safeguards where relevant. Abrupt discontinuation may cause harm, especially in epilepsy. The pharmacist should ensure counselling and prompt prescriber or specialist follow-up.

Reference: BNF; MHRA Drug Safety Update