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Gabapentin renal dosing — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentGabapentin renal dosingGPhC CRA

A patient with eGFR 22 mL/min/1.73 m² is prescribed gabapentin 300 mg three times daily for neuropathic pain. He reports increasing drowsiness and unsteadiness. What is the most appropriate action?

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Correct answer: C — Query dose suitability because gabapentin needs renal dose adjustment

Gabapentin is renally cleared and requires dose adjustment in renal impairment. Drowsiness and ataxia can indicate excessive exposure. The prescriber should review dose and ongoing need.

Reference: BNF