Valproate safety — GPhC CRA MCQ
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Correct answer: A — Supply with urgent referral for specialist review and pregnancy prevention counselling
Valproate has major teratogenic and neurodevelopmental risks. Women and girls of childbearing potential require specialist oversight and pregnancy prevention measures where valproate is used. Abrupt cessation in epilepsy may cause seizures, so urgent specialist review is needed rather than unilateral stopping.
Reference: BNF; MHRA Drug Safety Update