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ACE inhibitor and potassium supplement — GPhC CRA MCQ

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ModerateDrug InteractionsACE inhibitor and potassium supplementGPhC CRA

A 71-year-old woman taking ramipril is prescribed potassium chloride MR tablets after a hospital admission. Her latest potassium is 5.0 mmol/L. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: CIncreased hyperkalaemia risk

ACE inhibitors can increase serum potassium. Potassium supplements can therefore increase hyperkalaemia risk, especially in older patients or renal impairment. The indication and recent U&Es should be confirmed.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment