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GLP-1 gastrointestinal effects — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsGLP-1 gastrointestinal effectsGPhC CRA

A woman starts semaglutide for type 2 diabetes and weight management under specialist review. She asks whether severe persistent abdominal pain with vomiting is expected. What monitoring is required?

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Correct answer: E — Seek urgent medical advice because pancreatitis must be considered

GLP-1 receptor agonists commonly cause gastrointestinal effects, but severe persistent abdominal pain with vomiting warrants urgent assessment for pancreatitis or other pathology. Dose escalation should not continue during concerning symptoms. The prescriber should review treatment.

Reference: BNF