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SGLT2 sick day advice — GPhC CRA MCQ

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HardEndocrine TherapeuticsSGLT2 sick day adviceGPhC CRA

A 57-year-old woman takes dapagliflozin for type 2 diabetes. She has vomiting, poor oral intake and abdominal pain. Her home glucose is 9 mmol/L. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BStop dapagliflozin temporarily and seek urgent assessment for possible ketoacidosis

SGLT2 inhibitors can cause euglycaemic diabetic ketoacidosis, particularly during acute illness, fasting or dehydration. Abdominal pain and vomiting are concerning even when glucose is not very high. Urgent medical assessment and ketone testing are appropriate.

Reference: BNF; MHRA Drug Safety Update