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NSAID and DOAC — GPhC CRA MCQ

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EasyDrug InteractionsNSAID and DOACGPhC CRA

A patient taking apixaban asks to buy diclofenac tablets for acute knee pain. He has no gastroprotection. What is the most important interaction to flag?

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Correct answer: B — Increased bleeding risk with NSAID and anticoagulant combination

NSAIDs increase bleeding risk and gastrointestinal harm, which is compounded by anticoagulants such as apixaban. The pharmacist should recommend safer analgesia or referral. The patient should be counselled on signs of bleeding.

Reference: BNF