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DPP-4 inhibitor pancreatitis — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsDPP-4 inhibitor pancreatitisGPhC CRA

A patient taking sitagliptin asks about new severe abdominal pain radiating to the back with vomiting. He has no diarrhoea. What is the most appropriate action?

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Correct answer: D — Refer urgently because pancreatitis is a possible adverse effect

Severe abdominal pain with vomiting may indicate pancreatitis, a recognised rare adverse effect with DPP-4 inhibitors. Urgent medical assessment is appropriate. Symptomatic treatment alone would be unsafe.

Reference: BNF