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Ciprofloxacin and warfarin — GPhC CRA MCQ

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ModerateDrug InteractionsCiprofloxacin and warfarinGPhC CRA

A patient taking warfarin for a mechanical valve is prescribed ciprofloxacin for prostatitis. He asks whether he should inform the anticoagulation clinic. What is the most important interaction to flag?

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Correct answer: D — Ciprofloxacin can increase anticoagulant effect and bleeding risk

Quinolone antibiotics can alter anticoagulant control in patients on warfarin. INR monitoring and anticoagulation clinic advice are appropriate. Mechanical valve patients have high thrombotic risk, so management should be coordinated rather than self-adjusted.

Reference: BNF