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Digoxin toxicity — GPhC CRA MCQ

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HardCardiovascular TherapeuticsDigoxin toxicityGPhC CRA

An 82-year-old woman taking digoxin 125 micrograms daily has been started on amiodarone. Two weeks later she reports nausea, poor appetite and yellow-green visual disturbance. What is the most appropriate action?

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Correct answer: C — Refer urgently for digoxin level, U&Es and clinical assessment

Amiodarone can increase digoxin concentrations and the symptoms suggest digoxin toxicity. Older patients and those with renal impairment are at increased risk. Urgent assessment, digoxin level and U&Es are appropriate.

Reference: BNF